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Top Stories 27th
Annual Convention (7/25/08)
Convention
Lecture Legislation Journal
of the American Naturopathic Medical Association (JANMA) Facts |
ANMA ONLINE REFERENCES Volume 9 Number 2
Prostate Problems & Elevated Estrogen
By: Mike Menkes, BA, LMT REFERENCES 1. Induction of apoptosis in human prostate cancer cell line, PC3, by3,3'-diindolylmethane through the mitochondrial pathway. www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15328526. 2. Lee J. MD. Hormone Balance for Men: What your doctor may not tell you about prostate health and natural hormone supplementation. http://www.johnleemd.net 3. Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells.www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11420705. 4. Therapeutic activity of 3,3'-diindolylmethane on prostate cancer in an in vivo model. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15305338 5. http://www.johnleemd.com/store/prostate_cancer.html 6. What are the current treatment options for prostrate cancer? http://www.infoaging.org/d-prost-5-treatment.html 7. http://www.johnleemd.com/store/male_hormone.html
Benefits of a Special Sea Cucumber Extract inAnti-angiogenic Therapy and RTK Inhibition For Cancer
By: Tsu-Tsair Chi, N.M.D., Ph.D. REFERENCES 1. Benn SI, Whitsitt JS, Broadley KN, Nanney LB, Perkins D, He L, Patel M, Morgan JR, Swain WF, Davidson JM. Particle-mediated gene transfer with transforming growth factor-beta1 cDNAs enhances wound repair in rat skin. J Clin Invest 1996; 98: 2894-902. 2. Yamamoto S, et al. Expression of vascular endothelial growth factor (VEGF) during folliculogenesis and corpus luteum formation in the human ovary. Gynecol Endocrinol 1997; 11: 371-81 3. Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995; 1:27-31. 4. Eckhardt, Gail. Angiogenesis Inhibitors as Cancer Therapy. Hospital Practice 1999; 34(1):63. <http://www.hosppract.com/issues/1999/01/eckhardt.htm> March 30, 2005. 5. Viera and Mourao. Occurrence of a unique fucose-branched chondroitin sulfate in the body wall of a sea cucumber. J Biol Chem 1988; 263:18176-18183. 6. Findlay J and Anand Daljeet. Frondogenin, a new Aglycone from the sea cucumber cucumaria frondosa. J Natural Products 1984; 47(2):320-24. 7. Tong Y, Zhang X, Tian F, Yi Y, Xu Q, Li L, Tong L, Lin L, Ding J. Philinopside a, a novel marine-derived compound possessing dual anti-angiogenic and anti-tumor effects. Int J Cancer 2005; 114(6):843-53. 8. Angiogenesis. Angiogenesis Foundation. <http://www.angio.org/patients/cancer/cancer.html> March 30, 2005. 9. Folkman J. Tumor angiogenesis: Therapheutic Applications. N Engl J Med 1971; 285:82. 10. "FDA Approves First Angiogenesis Inhibitor to Treat Colorectal Cancer." U.S. Food and Drug Administration FDA News. February 26, 2004. <http://www.fda.gov/bbs/topics/NEWS/2004/NEW01027.html> March 16, 2005 11. "Gleevec Approved for First Line Treatment of Chronic Myeloid Leukemia (CML)." U.S. Food and Drug Administration FDA News. December 20, 2002. <http://www.fda.gov/bbs/topics/NEWS/2002/NEW00860.html> March 16, 2005 12. "FDA Approves New Drug for the Most Common Type of Lung Cancer." U.S. Food and Drug Administration FDA News. November 19, 2004. <http://www.fda.gov/bbs/topics/NEWS/2004/NEW01139.html> March 16, 2005 13. "FDA Statement on Iressa." U.S. Food and Drug Administration. FDA News. December 17, 2004. <http://www.fda.gov/bbs/topics/news/2004/new01145.html > April 6, 2005 14. "FDA approves Erbitux for olorectal cancer." U.S. Food and Drug Administration. FDA news. February 12, 2004. <http://www.fda.gov/bbs/topics/NEWS/2004/NEW01024.html> April 14, 2005. 15. "Top health stories of 2004." Harvard Health Letter. December 2004. 16. "Clinical trial shows SU11248 benefits more than half of patients with gastrointestinal tumors resistant to Gleevec." Dana Farber Cancer Institute. June 8, 2004. <http://www.dfci.harvard.edu/abo/news/press/060804.asp> April 11, 2005.
Essential Terms For Understanding Fats By: Steven Brynoff
Alpha-Linolenic Acid - an omega-3 found in canola, soy, walnuts and flaxseed that our bodies can convert to EPA and DHA. Bad Fats - Saturated fats and trans fatty acids are considered bad fats because of their link to elevated cholesterol and coronary risk. Cholesterol - A waxy, fat-like compound belonging to a class of molecules called steroids. Cholesterol is necessary for the formation and maintenance of cell membranes, and the manufacture of hormones, bile salts and vitamin D. The body makes some cholesterol, the rest comes from dietary animal products such as red meat, poultry eggs and milk products. Desirable levels should be below 200 mg/dL. DHA - An omega-3 EFA, docosahexaenoic acid, a key fish fat. Derives from alpha-linolenic acid. EPA - An omega-3 EFA, eicosapentaenoic acid, a key fish fat. Derives from alpha-linolenic acid. Essential Fatty Acids (EFAs) - There are two groups of polyunsaturated fats that your body cannot make: omega-3s and omega-6s. Because of this, you need a dietary source for optimal wellness. Gamma linolenic acid (GLA) - An omega-6 fatty acid that the body converts to a hormone-like substance called prostaglandin E1 (PGE1), may possess anti-inflammatory properties. Good Fats - Monounsaturated fats and some polyunsaturated fats are considered the 'good fats.' HDL - Known as 'good' cholesterol, this carrier molecule actually carries cholesterol away from the arteries and delivers it to the liver for processing and excretion out of the body. Levels should be above 45 mg/dL. LDL - Known as 'bad' cholesterol, too much of this carrier molecule can contribute to atherosclerosis and increase the risk of heart attack and stroke. Levels should be below 130 mg/dL Linoleic Acid - a common omega-6 EFA. Lipoproteins - Cholesterol doesn't dissolve in the blood, so it needs a carrier molecule. There are three main kinds - LDLs (low-density lipoproteins - these are the bad ones), HDLs (high-density lipoproteins - these are the good ones), and VLDLs (very low-density lipoproteins - these convert to LDLs). Monounsaturated Fats - Considered a good fat that can help lower blood cholesterol. These generally remain liquid at room temperature but may solidity in the refrigerator. Avocados and nuts are good sources. Omega-3s - A class of EFAs, polyunsaturated fatty acids, they are generally heart-friendly (decreasing the risk of coronary artery disease) and anti-inflammatory. They also appear to lower high blood pressure. Alpha-linolenic acid is a common omega-3 fat. Others that fall into this category include EPA and DHA. Common sources include flaxseeds, flax oil, pumpkin seeds, walnuts, salmon, mackerel, herring, trout and tuna. Omega-6s - A class of EFAs, polyunsaturated fatty acids. Linoleic acid (LA) is a common omega-6 fat. Others that fall into this category include arachidonic acid (AA), gamma linolenic acid (GLA) and dihomogamma linolenic acid (DGLA). Common sources for these include corn oil, sunflower oil and soybean oil. Polyunsaturated Fats - The 'in between' fats that have some good and some bad properties. These are usually liquids at room temperature and in the refrigerator. Good sources include vegetable oils, such as safflower, corn, sunflower, soy and cottonseed oils. Ratio LDL to HDL - This ratio should be below 3. Ratio Omega-6 to Omega-3s - Each EFA is necessary, but Americans do not get nearly enough omega-3. Currently Americans consume a ratio of 20+ to 1 omega-6 to omega-3 fats. It is recommended that we reduce the omega-6s and increase our omega-3s to a 4 to 1 ratio (depending on which expert you listen to). Ratio Total Cholesterol to HDL - This ratio should be below 4.5. Saturated Fats - The bad fats which raise LDL (bad) cholesterol and HDL (good) cholesterol. Trans Fatty Acids - Common, man-made fats produced by hudrogenating vegetable oils. This makes fats more solid and less likely to turn rancid, but they are very bad because they raise LDL (bad) cholesterol and lower HDL (good, protective) cholesterol. They may be found in hydrogenated or partially hydrogenated oils, margarines, fried foods and commercially baked goods and snack foods. Avoid these. Triglycerides - Calories from fats, carbohydrates, etc that are ingested but not used are converted to triglycerides and transported to fat cells to be stored for use later. Elevated levels have been linked to numerous conditions. Fasting levels should be below 150 mg/dL. Vitamin F - The EFAs linoleic, linolenic and arachidonic acid are collectively referred to as Vitamin F.
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